Research

Research and Development

Product Design

Supplement companies can easily design formulations in a few weeks by simply using commercially available raw materials. Restorative Formulations spends years of planning and testing to design specialty high potency products that are not currently available in the industry.

Lion’s Mane (Hericium erinaceum) Neuro Protectant

We have worked on a two-year research project with Matthew Robison, Ph.D. of US Botanical Safety Laboratory, along with two Ph.D. scientists from the University of North Carolina, to determine the diterpene derivatives of Lion’s Mane mushroom (Hericium erinaceum). This project included examining erinacine, a Hericium compound which has been tested in benchtop studies and shown to support nerve growth factor. We have isolated ten different HPLC chromatogram peaks of diterpene derivatives, which has never been done before.

We also researched and tested the optimal growing conditions and are now currently cultivating Lion’s Mane with the highest concentration of diterpene derivatives compared to any brand on the market. Lion’s Mane Neuro Protectant will launch in Fall 2018.

 

 

Hawthorn (Craetagus oxyacanthus) Vascular Protectant

Vitexin is a flavonoid and considered an important active compound found in hawthorn. We have tested flavonoids from hawthorn leaves, flowers, berries and extracts from three continents and found that the highest concentration of vitexins occur in the spring harvest of flowers in France.

African Snakeroot (Rauwolfia vomitoria) Cardiovascular Relaxant

Recognizing that this plant is endangered in India, we identified a new species of Rauwolfia that is plentiful and sustainable in Tanzania. We worked with independent research laboratories, using HPLC mass spectrometry to test reserpine content within a matrix of over ten different alkaloids.

Iodine-Thyroid Support

We have worked with three chemists and two independent laboratories to analyze whether iodine stays in its elemental form once it is dried. After extensive testing, including mass spectrometry, ion chromatography, x-ray fluorescence, and inductively coupled plasma mass spectrometry, we have found that dry iodine, once ingested, does not stay in it’s elemental form. We applied this new knowledge to the development of Iodine Px and Thyroid Px.